Indian Journal of Ophthalmology - Case Reports

OPHTHALMIC IMAGE
Year
: 2021  |  Volume : 1  |  Issue : 2  |  Page : 163-

Bilateral anterior blue dot and posterior coralliform cataract


Shana Sood, Sanjana Vatsa 
 Department of Cornea and Refractive Services, Dr. Agarwals' Eye Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Shana Sood
Department of Cornea and Refractive Services, Dr. Agarwals' Eye Hospital, 222, TTK Road, Chennai - 600 004, Tamil Nadu
India




How to cite this article:
Sood S, Vatsa S. Bilateral anterior blue dot and posterior coralliform cataract.Indian J Ophthalmol Case Rep 2021;1:163-163


How to cite this URL:
Sood S, Vatsa S. Bilateral anterior blue dot and posterior coralliform cataract. Indian J Ophthalmol Case Rep [serial online] 2021 [cited 2022 Dec 5 ];1:163-163
Available from: https://www.ijoreports.in/text.asp?2021/1/2/163/312339


Full Text



An 18-year-old male presented with bilateral anterior blue dot [Figure 1]a with posterior coralliform cataract [Figure 1]b and [Figure 1]c. Blue dot cataracts are associated with mutation in CRYBB2 gene coding for crystallin beta B2.[1] Coralliform cataract is a rare congenital cataract and characterized by stellate opacities; it is associated with mutation in the CRYGD gene coding for crystallin gamma D.[2],[3],[4] Colour vision was defective and fundus examination showed bilateral temporal disc pallor [Figure 1]d. Dilated evaluation is essential in cases of blue dot cataract to rule out other associated forms of cataract and disc evaluation with color vision is a must in such cases.{Figure 1}

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

References

1Litt M, Carrero-Valenzuela R, LaMorticella DM, Schultz DW, Mitchell TN, Kramer P, et al. Autosomal dominant cerulean cataract is associated with a chain termination mutation in the human β-crystallin gene CRYBB2. Hum Mol Genet 1997;6:665-8.
2Arora A, Reddy A, Francis P, Ionides A, Berry V, Moore A, et al. A CRYGD mutation is associated with familial coralliform cataract. Invest Ophthalmol Vis Sci 2004;45:374.
3Li F, Wang S, Gao C, Liu S, Zhao B, Zhang M, et al. Mutation G61C in the CRYGD gene causing autosomal dominant congenital coralliform cataracts. Mol Vis 2008;14:378-86.
4Vanita V, Singh D. A missense mutation in CRYGD linked with autosomal dominant congenital cataract of aculeiform type. Mol Cell Biochem 2012;368:167-72.