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Year : 2023  |  Volume : 3  |  Issue : 2  |  Page : 524-525

Orbital metastasis of choriocarcinoma from a testicular malignant germ cell tumor: A late unfavorable prognostic sign

1 Ocular Oncology Service, Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey
2 Department of Ophthalmology, University of Health Science, Haseki Training and Research Hospital, Istanbul, Turkey
3 Department of Pathology, Yuksek Ihtisas University School of Medicine, Ankara, Turkey
4 Department of Pathology, Hacettepe University School of Medicine, Ankara, Turkey İstanbul, Turkey

Correspondence Address:
Hayyam Kiratli
Professor of Ophthalmology, Ocular Oncology Service, Hacettepe University School of Medicine, Sihhiye - 06100, Ankara, Turkey İstanbul
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJO.IJO_2771_22

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A 43-year-old man presented with a painful left proptosis 6 years after he had had orchiectomy for a mixed germ cell tumor. He also previously developed pulmonary and brain metastases, which were treated with chemotherapy and radiotherapy. Magnetic resonance imaging studies revealed an irregular mass confined to the left superior orbit. The neoplastic cells stained positive for human placental lactogen and sal-like protein 4 but negative for Alpha fetoprotein (AFP), CD30, and octamer binding transcription factor 3/4, compatible with metastatic choriocarcinoma. A painful mass located in the superior orbit in a young man must arouse the suspicion for a metastatic testicular carcinoma.

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