CASE REPORT |
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Year : 2023 | Volume
: 3
| Issue : 2 | Page : 441-444 |
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Variable response of sub-retinal hyper-reflective membranes to anti-vascular endothelial growth factor treatment in bilateral neo-vascular age-related macular degeneration: A case report
Debdulal Chakraborty, Soumen Mondal, Subhendu Boral, Asmita Saha
Department of Vitreoretina Services, Disha Eye Hospitals, Kolkata, West Bengal, India
Correspondence Address:
Debdulal Chakraborty Department of Vitreoretina Services, Disha Eye Hospitals, 88 Ghosh Para Road, Barrackpore, Kolkata - 700 120, West Bengal India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/ijo.IJO_2034_22
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Sub-retinal hyper-reflective material (SHRM) is an important spectral-domain optical coherence tomography biomarker in neo-vascular age-related macular degeneration (nAMD). The exact nature of SHRM is not known, but it may contain fluid, fibrin, blood, neo-vascular tissue, and so on. Although nAMD with avascular SHRM usually resolves with anti-vascular endothelial growth factor and is known to have better visual prognosis, those with vascular SHRM have significantly poor final vision. We present a unique case of nAMD with an avascular SHRM in the right eye and a vascular SHRM in the left eye and how the two eyes behaved with treatment over a period of 12 months.
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