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Year : 2023  |  Volume : 3  |  Issue : 2  |  Page : 441-444

Variable response of sub-retinal hyper-reflective membranes to anti-vascular endothelial growth factor treatment in bilateral neo-vascular age-related macular degeneration: A case report

Department of Vitreoretina Services, Disha Eye Hospitals, Kolkata, West Bengal, India

Correspondence Address:
Debdulal Chakraborty
Department of Vitreoretina Services, Disha Eye Hospitals, 88 Ghosh Para Road, Barrackpore, Kolkata - 700 120, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_2034_22

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Sub-retinal hyper-reflective material (SHRM) is an important spectral-domain optical coherence tomography biomarker in neo-vascular age-related macular degeneration (nAMD). The exact nature of SHRM is not known, but it may contain fluid, fibrin, blood, neo-vascular tissue, and so on. Although nAMD with avascular SHRM usually resolves with anti-vascular endothelial growth factor and is known to have better visual prognosis, those with vascular SHRM have significantly poor final vision. We present a unique case of nAMD with an avascular SHRM in the right eye and a vascular SHRM in the left eye and how the two eyes behaved with treatment over a period of 12 months.

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