| CASE REPORT |
|
| Year : 2023 | Volume
: 3
| Issue : 2 | Page : 393-395 |
|
|
Bilateral macular telangiectasias with macular edema in a patient on incessant diethylcarbamazine medication – A case report
Saurabh Agrawal
Sukriti Eye Clinic, Lucknow, Uttar Pradesh, India
Correspondence Address:
Saurabh Agrawal
Sukriti Eye Clinic, B-3, Kapoorthala Bagh, Kursi Road, Lucknow - 226 024, Uttar Pradesh
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/ijo.IJO_1950_22
|
|
|
Macular telangiectasia is characterized by bilateral alterations of the macular capillary network and neurosensory atrophy, but it is very rarely associated with macular edema. Presented here is a case with bilateral macular capillary telangiectasias with severe macular edema and subretinal fluid accumulation. Here, a proposed mechanism for the injury to the capillaries, causing telangiectasias and edema, is the toxicity of drug diethylcarbamazine, which the patient had been self-administering for lymphatic filariasis for 20 years. The drug at increased concentrations is known to accentuate free radical–mediated cellular injury by inhibiting the lipooxygenase pathway.
|
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
