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Year : 2023  |  Volume : 3  |  Issue : 2  |  Page : 274-277

Atypical presentation of calcific band keratopathy: A case report and literature review

1 Department of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel
2 Department of Ophthalmology, Sheba Tel HaShomer Medical Center, Ramat Gan, Israel

Correspondence Address:
Lee Goren
Department of Ophthalmology, Rabin Medical Center, Petah Tikva, 39 Jabotinsky St. 49100
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJO.IJO_2683_22

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To report an unusual presentation of calcific band keratopathy and to hypothesize what causes this presentation, as well as its management with ethylenediaminetetraacetic acid (EDTA) chelation using dipotassium-ethylenediaminetetraacetic acid (K2-EDTA). We have conducted a review of the literature on the pathogenesis and treatment of calcific band keratopathy while focusing on the role of hypercalcemia, dry eyes, and corneal exposure. A 53-year-old patient developed an atypical calcific band keratopathy attributed to her ocular and medical history, which included end-stage renal disease (ESRD), hypercalcemia, glaucoma, dry eyes, and chronic use of eye drops. Within two months after starting the administration of oral vitamin D supplements, white/grey opacities appeared on the patient's cornea, as well as hypercalcemia. The patient was instructed to desist vitamin D supplements. Superficial epithelial keratectomy with EDTA chelation using K2-EDTA was performed while abstaining from the limbal opacities. After a 30-day period, the patient's cornea remained clear, and no recurrence of corneal opacities was observed. To the best of our knowledge, this is the first published case that reports this type of unique presentation of calcific band keratopathy. The hypothesis for the reason of the unique clinical presentation of our case will be discussed.

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