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Year : 2023  |  Volume : 3  |  Issue : 1  |  Page : 259

Fish eye babies: Ichthyosis

Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Medical Research Foundation, Chennai, Tamil Nadu, India

Date of Web Publication20-Jan-2023

Correspondence Address:
Bipasha Mukherjee
Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Medical Research Foundation, 18 College Road, Chennai - 600 006, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_1102_22

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How to cite this article:
Mukherjee B, Sivaranjani P. Fish eye babies: Ichthyosis. Indian J Ophthalmol Case Rep 2023;3:259

How to cite this URL:
Mukherjee B, Sivaranjani P. Fish eye babies: Ichthyosis. Indian J Ophthalmol Case Rep [serial online] 2023 [cited 2023 Feb 1];3:259. Available from: https://www.ijoreports.in/text.asp?2023/3/1/259/368125

Ichthyosis refers to a group of rare dermatological condition characterized by dry, thickened, and scaly skin. The term is derived from the Greek word ichthys meaning fish. Ichthyosis can be inherited in an autosomal dominant (ichthyosis vulgaris), recessive (lamellar ichthyosis), or x-linked recessive fashion due to diverse genetic mutations. Ocular complications are usually related to the shortening of the anterior lamella of the eyelids leading to cicatricial ectropion, lagophthalmos, and exposure keratitis[1],[2][Figure 1].
Figure 1: (a) A child with ichthyosis vulgaris characterized by scaly skin lesions. Ocular manifestations are minimal. (b) A 10-month-old child with lamellar ichthyosis, exhibiting severe ectropion of all four eyelids. (c) Another child with lamellar ichthyosis with ectropion. (1d) The Same child as in (1c) after six months showing lagophthalmos after conservative management with skin emollients and oral retinoid

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Management consists of topical non-preserved artificial tears and petrolatum ointment. Long-term oral retinoids reduce scaling, discomfort, and disfigurement. Severe ectropion requires a full-thickness skin graft. Due to the generalized involvement of the skin, an autograft may be difficult. In those patients, allografts, mucous membrane, and human-engineered skin can be used.[3],[4],[5]

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

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Conflicts of interest

There are no conflicts of interest.

  References Top

Zachara MG, Drozdowski PH, Łątkowski IT. Surgical management of ichtyosis-related ectropion. Description of four cases and a literature review. J Plast Surg Hand Surg 2014;48:179-82.  Back to cited text no. 1
Al-Amry MA. Ocular manifestation of ichthyosis. Saudi J Ophthalmol 2016;30:39-43.  Back to cited text no. 2
Subramanian N, Nivean PD, Alam MS. Combined medical and surgical management for cicatricial ectropion in lamellar ichthyosis: A report of three cases. Indian J Ophthalmol 2020;68:2615-7.  Back to cited text no. 3
[PUBMED]  [Full text]  
Das S, Honavar SG, Dhepe N, Naik M. Maternal skin allograft for cicatricial ectropion in congenital ichthyosis. Ophthal Plast Reconstr Surg 2010;26:42-3.  Back to cited text no. 4
Culican SM, Custer PL. Repair of cicatricial ectropion in an infant with harlequin ichthyosis using engineered human skin. Am J Ophthalmol 2002;134:442-3.  Back to cited text no. 5


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