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Year : 2022  |  Volume : 2  |  Issue : 4  |  Page : 977-979

Orbital metastasis from breast carcinoma presenting as an osteoblastic lesion

1 Department of Ophthalmology, Royal Adelaide Hospital, Port Road; Discipline of Ophthalmology and Visual Sciences, University of Adelaide, North Terrace, South Australia
2 Department of Radiology, Royal Adelaide Hospital, Adelaide, South Australia, Australia

Correspondence Address:
Dr. Raghav Goel
Department of Ophthalmology, Royal Adelaide Hospital, Port Road, Adelaide
South Australia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_463_22

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A 66-year-old female presented with a swollen and itchy eyelid for 4 weeks. A computed tomography (CT) scan revealed a lesion epicentered in the greater wing of the sphenoid and anterior lateral and superior orbital walls, predominantly showing osteoblastic features. Magnetic resonance imaging (MRI) demonstrated further calvarial and pachymeningeal involvement. Biopsy of the lesion demonstrated a poorly differentiated carcinoma. A distant history of breast cancer (20 years) prompted specific immunochemistry that confirmed breast carcinoma metastases. Staging positron emission tomography-computed tomography (PET) revealed multisystem spread. This report highlights the fact that breast carcinoma metastasis may rarely present with a predominantly osteoblastic lesion in the orbit.

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