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CASE SERIES
Year : 2022  |  Volume : 2  |  Issue : 4  |  Page : 897-899

Anterior nodular scleritis – tuberculosis or granulomatosis with polyangiitis? A series of three cases


1 Deparment of Ophthalmology, Kalinga Institute of Medical Sciences; Department of Ophthalmology, Vision Care, Centre for Retina, Bhubaneswar, Odisha, India
2 Department of Ophthalmology, Uvea, Sankara Nethralaya, Kolkata, West Bengal, India
3 Deparment of Obstetrics and Gynaecology, Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India
4 Deparment of Clinical Immunology and Rheumatology, Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India
5 Department of Ophthalmology, Vision Care, Centre for Retina, Bhubaneswar, Odisha, India

Correspondence Address:
Dr. Nidhi Sinha
M-1, Samanta Vihar, Near NALCO Chowk, Bhubaneswar - 751 017, Odisha
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_751_22

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Scleritis is a chronic destructive inflammatory disorder. It has various systemic associations, including granulomatosis with polyangiitis (GPA). However, anterior nodular scleritis being the initial manifestation of GPA is rare. Being in an endemic country of tuberculosis (TB), it is imperative to exclude any possibility of active or latent TB before institution of immunosuppressive agents. Similarly, the vice versa should be kept in mind. We present three cases of persistent anterior nodular scleritis even after treatment with antitubercular treatment (ATT). Subsequent recurrences led to the evaluation and diagnosis of GPA with multisystem involvement. Treatment with immunosuppressive therapy led to successful recovery.


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