|Year : 2022 | Volume
| Issue : 3 | Page : 860
Eye inside iris
Radha Shanthi1, Chitaranjan Mishra2, Kuppamuthu Dharmalingam3, Ramasamy Krishnadas4
1 Department of Pathology, Aravind Eye Hospital, Madurai, Tamil Nadu, India
2 Department of Vitreo-Retina, Aravind Eye Hospital, Madurai, Tamil Nadu, India
3 Department of Proteomics, Aravind Medical Research Foundation, Dr. G. Venkataswamy Eye Research Institute, Aravind Eye Care System, Madurai, Tamil Nadu, India
4 Department of Glaucoma, Aravind Eye Hospital, Madurai, Tamil Nadu, India
|Date of Web Publication||16-Jul-2022|
Dr. Chitaranjan Mishra
Department of Vitreo-Retinal Services, Aravind Eye Hospital, Anna Nagar, Madurai - 625 020, Tamil Nadu
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Shanthi R, Mishra C, Dharmalingam K, Krishnadas R. Eye inside iris. Indian J Ophthalmol Case Rep 2022;2:860
During the histopathological interpretation of a cadaveric iris tissue for the study of pseudoexfoliation syndrome, an interesting observation was captured under the microscope. A single endothelial cell lining the inner wall of a blood vessel [[Figure 1]a, arrow mark] and one pericyte [[Figure 1]a, star mark] were seen. Under the background of eosinophilic collagen material, these structures gave the visual appearance of an eye. The pigment granules from the iris pigment epithelium can be noticed in the larger specimen of the tissue [[Figure 1]b, triangles]. Presence of the endothelial cell and pericyte surrounding the lumen helped in the identification of the iris blood vessel and differentiated this from the pigment granules. Artistic impressions in tissue slides should be observed for their pathological significance before declaring them as artefacts.
|Figure 1: (a) Histopathological examination of the iris tissue with blood vessel showing endothelial cell (white arrow mark) and pericyte (white star mark), simulating an eye. (b) The larger specimen of the tissue showing pigment granules from the iris pigment epithelium (white triangles).|
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| References|| |
Freddo TF, Raviola G. The homogeneous structure of blood vessels in the vascular tree of Macaca mulatta iris. Invest Ophthalmol Vis Sci 1982;22:279-91.