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CASE REPORT
Year : 2022  |  Volume : 2  |  Issue : 3  |  Page : 647-648

Bilateral hypopyon corneal ulcers in pancreatic carcinoma


1 Department of Ophthalmology, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry, India
2 Department of Internal Medicine, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry, India
3 Department of Medical Oncology, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry, India

Correspondence Address:
Dr. Geeta Behera
Department of Ophthalmology, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry - 605006
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_1720_21

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A 39-year-old woman on palliative chemotherapy for pancreatic carcinoma presented with painful bilateral vision loss. On examination, she had large bilateral corneal ulcers with hypopyon, with corneal and conjunctival xerosis. She was extremely malnourished. Investigations revealed macrocytic anemia with pancytopenia and hypoproteinemia suggestive of pancreatic enzyme insufficiency (PEI). Microbiology reported Pseudomonas aeruginosa infection that was sensitive to ceftazidime. Treatment with topical ceftazidime and oral vitamin A and B12 supplementation (therapeutic doses) led to rapid resolution of the ulcers in 4 weeks. Xerophthalmia with secondary keratitis due to malnutrition from pancreatic carcinoma is hitherto unreported but can be treated successfully with timely identification.


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