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Year : 2022  |  Volume : 2  |  Issue : 2  |  Page : 494-496

Masquerade versus masquerade: An unusual presentation of systemic B-cell lymphoma misdiagnosed as giant cell arteritis - A case report

Department of Ophthalmology, University Hospital Southampton, Tremona Road, Southampton- SO16 6YD, United Kingdom

Correspondence Address:
Sajjad Abbas
University Hospital Southampton, Tremona Road, Southampton- SO16 6YD
United Kingdom
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_2808_21

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This is an atypical uniocular presentation of systemic diffuse large B-cell lymphoma. An 80-year-old Caucasian female presented with acute left visual loss, anorexia, headache, and jaw pain with disk swelling. Systemic steroids for giant cell arteritis were started despite negative temporal artery biopsy. Later, an inferior exudative retinal detachment developed. Lytic skull lesions were eventually seen on magnetic resonance imaging. Diffuse large B-cell lymphoma was diagnosed postmortem. This is the second documented case of unilateral serous retinal detachment with no uveitis/pseudouveitis or choroidal infiltrate due to lymphoma. It demonstrates pitfalls of pattern recognition when pieces of the jigsaw do not fit.

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