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CASE REPORT
Year : 2022  |  Volume : 2  |  Issue : 2  |  Page : 419-421

Possible IgG4-related disease in a case of necrotizing scleritis


1 Senior Resident, Giridhar Eye Institute, Ernakulam, Kerala, India
2 Department of Orbit, Oculoplasty and Ocular Oncology, Giridhar Eye Institute, Ernakulam, Kerala, India
3 Department of Cornea and Refractive Surgery Services, Giridhar Eye Institute, Ernakulam, Kerala, India
4 Department of Vitreoretina, Giridhar Eye Institute, Ernakulam, Kerala, India
5 Ocular Pathology, Sankara Nethralaya, Chennai, India
6 Department of Rheumatology, Centre For Arthritis And Rheumatism Excellence (CARE), Nettoor, Cochin, India

Correspondence Address:
Marian Pauly
Department of Orbit, Oculoplasty and Ocular Oncology, Giridhar Eye Institute, Kochi, Kerala - 682 020
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_1455_21

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Necrotizing scleritis can be a diagnostic and therapeutic challenge. We present a case of a 51-year-old female, who had necrotizing scleritis treated for 9 years with intermittent corticosteroid therapy. In view of its recalcitrant nature, she underwent scleral biopsy, which revealed histopathological features suggestive of IgG4- related disease. This case report highlights the importance of including IgG4-related disease as a differential diagnosis of scleritis and the role of scleral biopsy as a diagnostic tool in unresponsive cases.


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