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Year : 2022  |  Volume : 2  |  Issue : 2  |  Page : 379-381

Recurrent herpes simplex virus nummular keratitis in a case of irritable bowel syndrome and seronegative ankylosing spondylitis

1 The Cornea Institute, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, India
2 Jhaveri Microbiology Centre, LV Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, India
3 Wagh Eye Clinic, Pune, Maharashtra and Ruby Hall Clinic, Grant Medical Foundation, Pune, Maharashtra, India

Correspondence Address:
Somasheila I Murthy
L.V. Prasad Eye Institute, L.V. Prasad Marg, Banjara Hills, Hyderabad - 500 034, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_2575_21

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A 35-year-old male presented with a 16-month history of left-eye recurrent redness, photophobia, and blurring in his left eye. Systemically, he suffered from irritable bowel syndrome and HLA-B27-negative spondyloarthropathy. The cornea showed multiple nummular epithelial and anterior stromal lesions. The aqueous sample was positive for herpes simplex virus-1 DNA (glycoprotein-D gene) by polymerase chain reaction. The lesions resolved with oral acyclovir and topical dexamethasone 0.01% in tapering doses; however, he continued to have recurrent periodic redness even at 1 year. We hypothesize that coexisting systemic immune-mediated conditions may have a role in altering the disease course leading to its prolongation in our case.

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