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Year : 2022  |  Volume : 2  |  Issue : 2  |  Page : 345-347

Endocrine mucin-producing sweat gland carcinoma mimicking meibomian gland carcinoma

Department of Ophthalmology, Sir J. J Hospital and Grant Government Medical College, Mumbai, Maharashtra, India

Correspondence Address:
Sumeet T Lahane
Sir J. J Hospital and Grant Government Medical College, Mohd. Ali Road, Byculla, Mumbai - 400 008, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_1299_21

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Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is a rare adnexal tumor of the skin with immunoexpression and neuroendocrine differentiation. It can be easily misdiagnosed as a meibomian gland tumor due to its prevalence in the Indian subcontinent over EMPSGC. It has a predilection for the skin of the eyelid and elderly females. It is histologically and immunohistochemically analogous to solid papillary carcinoma of the breast/endocrine ductal carcinoma in situ with a nodular, solid, papillary, and/or cribriform architecture, neuroendocrine differentiation, and mucin production. We describe a case of EMPSGC clinically mimicking meibomian gland carcinoma which was confirmed on immunohistochemistry and histopathological diagnosis.

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