• Users Online: 143
  • Print this page
  • Email this page

 Table of Contents  
Year : 2022  |  Volume : 2  |  Issue : 1  |  Page : 296-297

Sebaceous mantleoma: A rare benign neoplasm

Aravind Eye Hospital, Puducherry, India

Date of Submission08-Aug-2020
Date of Acceptance27-Mar-2021
Date of Web Publication07-Jan-2022

Correspondence Address:
Dr. Anupama Joy
Aravind Eye Hospital, Cuddalore Main Road, Thavalakuppam, Puducherry - 605 007
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_2568_20

Rights and Permissions

Keywords: Benign neoplasm, mantle, sebaceous mantleoma

How to cite this article:
Rajagopalan J, Joy A, Yadalla D. Sebaceous mantleoma: A rare benign neoplasm. Indian J Ophthalmol Case Rep 2022;2:296-7

How to cite this URL:
Rajagopalan J, Joy A, Yadalla D. Sebaceous mantleoma: A rare benign neoplasm. Indian J Ophthalmol Case Rep [serial online] 2022 [cited 2022 Aug 14];2:296-7. Available from: https://www.ijoreports.in/text.asp?2022/2/1/296/334938

A 62-year-old female presented with a painless, gradually progressive mass in the upper lid of the right eye for 4 years. There was no significant past history or history of any swelling elsewhere in the body. Her uncorrected visual acuity was hand movements in the right eye. On examination a firm nontender mass of size 5 × 5 × 3 cm confined to the right upper eyelid involving the tarsus with necrotic areas present within and excoriation of the lower lid and periorbital skin was noted [Figure 1]a and [Figure 1]b. Excision of the tumor with a margin clearance of 5 mm was done. Histopathological examination revealed cords and nests of undifferentiated cells radiating from follicles with sebocytes and ducts suggestive of sebaceous mantleoma [Figure 1]c and [Figure 1]d. Immunohistochemistry was not done. Lid reconstruction was done using the Cutler Beard technique. On follow-up of 1 year, no recurrence was noted.
Figure 1: (a and b) Firm nontender mass measuring 5 × 5 × 3 cm involving the entire upper eyelid and tarsus with necrotic areas within the mass and excoriation of periorbital skin. (c) Cords and nests of undifferentiated cells radiating from follicles with sebocytes and ducts (arrow). (d) Folliculocentric basaloid proliferation with sebocytes and ducts

Click here to view

  Discussion Top

A sebaceous mantle is an atrophic form of the sebaceous gland during the resting phase of its cycle which is observed during prepuberty and menopause/andropause.[1] In the resting phase of the cycle, the mantle arises from the infundibulum of the hair follicle and then drops down aside in the form of a mantle or skirt.[1],[2] It is presumed that sebaceous glands involute to form undifferentiated mantles.[2] An adenoma arising from these mantle differentiations is termed as mantle adenoma or mantleoma. Histopathologically, it is composed of cords of basaloid cells that hang downward, just like a skirt, from the junction of the follicular infundibulum and isthmus.[1],[2] On immunohistochemistry they express CD117, CD8, AR, and GATA 3. CD8 which cross-reacts with cytokeratin 15 is more specific to follicle bulges and sebaceous mantles. CK20 positive dendritic cells in addition to CK7 positive cells are admixed in this neoplasm.[1] These neoplasms are completely benign and rarely recur.[2]

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

  References Top

Goto K, Misago N, Sumiya N, Ishikawa Y. Sebaceous mantleoma (mantle adenoma): Reappraisal of the myth of the problematic benign neoplasm with sebaceous mantle differentiation. J Cutan Pathol 2016;43:1050-5.  Back to cited text no. 1
Eisen DB, Michael DJ. Sebaceous lesions and their associated syndromes: Part I. J Am Acad Dermatol 2009;61:549-60; quiz 561-2.  Back to cited text no. 2


  [Figure 1]


Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
Access Statistics
Email Alert *
Add to My List *
* Registration required (free)

  In this article
Article Figures

 Article Access Statistics
    PDF Downloaded33    
    Comments [Add]    

Recommend this journal