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Year : 2022  |  Volume : 2  |  Issue : 1  |  Page : 183-185

Progressive optic neuropathy secondary to JAK2 mutation-positive myeloproliferative neoplasm

1 Associate Consultant, Sri City Sankara Nethralaya, Chittoor, Andhra Pradesh, India
2 Director, Department of Neuro-Ophthalmology, Sankara Nethralaya, Chennai, Tamil Nadu, India
3 Department of Radiology, Sankara Nethralaya, Chennai, Tamil Nadu, India
4 Department of Neurology, Vijaya Health Care, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Swetha Komma
Department of Neuro-Ophthalmology, Sankara Nethralaya, No.41 (Old No.18), College Road, Chennai - 600 006, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_768_21

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We describe a 25-year-old male presenting with chronic papilledema due to cerebral venous sinus thrombosis (CVST) and was found to have a myeloproliferative disorder with JAK2 mutation. All measures to salvage vision were unfruitful from transverse sinus stenting, thecoperitoneal shunt to optic nerve sheath fenestration. This case illustrates the importance of screening for JAK2 mutation in patients with CVST and abnormal blood counts.

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