|Year : 2021 | Volume
| Issue : 4 | Page : 855
Zonules imaged by anterior segment optical coherence tomography in a patient with traumatic aniridia
Noreen Shaikh, Michael L Cooper, David J Ramsey
Department of Ophthalmology, Lahey Hospital & Medical Center, Tufts University School of Medicine, 1 Essex Center Drive, Peabody, MA 01960, USA
|Date of Web Publication||09-Oct-2021|
Dr. David J Ramsey
Department of Ophthalmology, Lahey Hospital & Medical Center, Tufts University School of Medicine, 1 Essex Center Drive, Peabody, MA 01960
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Shaikh N, Cooper ML, Ramsey DJ. Zonules imaged by anterior segment optical coherence tomography in a patient with traumatic aniridia. Indian J Ophthalmol Case Rep 2021;1:855
|How to cite this URL:|
Shaikh N, Cooper ML, Ramsey DJ. Zonules imaged by anterior segment optical coherence tomography in a patient with traumatic aniridia. Indian J Ophthalmol Case Rep [serial online] 2021 [cited 2021 Oct 26];1:855. Available from: https://www.ijoreports.in/text.asp?2021/1/4/855/327714
A 68-year-old male with traumatic aniridia [Figure 1]a 20 years prior underwent anterior segment-optical coherence tomography (AS-OCT). In the scan in [Figure 1]b, the lack of signal attenuation by the iris allows visualization of the lens–zonule interface. The zonules appear as thin, hyperreflective bands extending from the ciliary body to the equator of the lens. Although the zonules are below the axial scanning resolution of the AS-OCT machine, being only 1–2 μm thick, they are captured in the tomographic image by virtue of detecting the interference pattern created by the scatter of infrared light off their surfaces.
|Figure 1: (a) Slit-lamp photograph illustrating the lens and its zonules en face by means of retroillumination. The white arrow represents the location of the tomographic cross-section. (b) AS-OCT scan (RTVue-XR Avanti, Optovue, California) illustrating the lens–zonule interface. The mirror image of the cornea cross-section intrudes into the scan because of the depth of imaging required. Scale bars: 500 μm|
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The authors thank Dr. Jeffrey Marx, Dr. Shiyoung Roh, Amy Swan, Timothy Tivnan, David H. Pfennighaus, and Carol Spencer, Lahey Hospital Librarian, for research support.
Financial support and sponsorship
D.J.R. is supported by a grant from the Myles and Gertrude Hanson Foundation, Providence, Rhode Island, USA, and by the Harry N. Lee Family Chair in Innovation, Lahey Hospital & Medical Center, Beth Israel Lahey Health, Peabody, Massachusetts, USA.
Conflicts of interest
There are no conflicts of interest.
| References|| |
Los LI, van der Worp RJ, van Luyn MJ, Hooymans JM. Presence of collagen IV in the ciliary zonules of the human eye: An immunohistochemical study by LM and TEM. J Histochem Cytochem 2004;52:789-95.