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CASE REPORT
Year : 2021  |  Volume : 1  |  Issue : 4  |  Page : 720-723

An unusual case of juvenile xanthogranuloma presenting as a subconjunctival nodule with review of literature


1 Department of Oculoplasty and Ocular Oncology Services, Dr. R.P. Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
2 Department of Pediatric Ophthalmology Services, Chacha Nehru Bal Chikitsalya, Geeta Colony, New Delhi, India
3 Department of Ocular Pathology Services, Dr. R.P. Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Dr. Meenakshi Wadhwani
Department of Pediatric Ophthalmology Services, Room No 228, Chacha Nehru Bal Chikitsalya, Geeta Colony, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_3587_20

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Juvenile xanthogranuloma (JXG) is a benign histiocytic disorder that belongs to the non-Langerhans cell group. Extracutaneous involvement in the eye usually involves the iris and presents as recurrent spontaneous episodes of hyphema or secondary glaucoma. A 3-year-old child presented with a subconjunctival mass in the left eye and concurrent scalp nodules. Ultrabiomicroscopic examination showed a moderately reflective episcleral mass with extension into cornea but no scleral involvement. Histopathology of the excised subconjunctival mass showed a dense infiltrate of polygonal/spindle mononuclear cells with moderate amounts of cytoplasm and scattered Touton giant cells, suggestive of JXG. Systemic evaluation did not reveal any other sites of involvement. Postoperatively, the patient was treated with topical steroids. At last follow-up 2.5 years, the patient is free on any recurrence.


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