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Year : 2021  |  Volume : 1  |  Issue : 3  |  Page : 596-598

Bilateral external ophthalmoplegia due to uremia in Goodpasture syndrome: A case report

1 Liberia Eye Center (L V Prasad Eye Institute Liberia Inc) John F Kennedy Memorial Medical Center, Monrovia, Liberia
2 Aulakh Simranjeet (MS), Fellow in Pediatric Ophthalmology and Strabismus, Jasti V Ramanamma Children's Eye Care Centre, Kallam Anji Reddy Campus, Hyderabad, India
3 Megha S. Uppin, MD Associate Professor, Department of Pathology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, India

Correspondence Address:
Dr. Niranjan K Pehere
Head, Liberia Eye Center (L V Prasad Eye Institute Liberia Inc), John F Kennedy Memorial Medical Center, Monrovia - - 1000
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_2727_20

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Several ophthalmic manifestations have been reported in patients with uremia due to chronic kidney disease (CKD). These include chronic sore eyes, ischemic optic neuropathy, and retinal detachment. In this case report, we discuss a patient of Goodpasture syndrome undergoing hemodialysis for CKD who presented with a complaint of diplopia. The patient had bilateral near-total external ophthalmoplegia, which initially progressed and remained constant at the last follow-up. The patient was neurologically stable with normal neuroimaging; however, his serum creatinine and blood urea levels remained persistently elevated despite regular hemodialysis. After considering several differential diagnoses, we finally arrived at a diagnosis of bilateral external ophthalmoplegia secondary to uremia and propose potential mechanisms for its pathogenesis.

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