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OPHTHALMIC IMAGE
Year : 2021  |  Volume : 1  |  Issue : 3  |  Page : 454

Persistent fetal vasculature with membranous cataract


State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China

Date of Web Publication02-Jul-2021

Correspondence Address:
Dr. Weirong Chen
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 7 Jinsui Road, Guangzhou - 510 623
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_3677_20

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How to cite this article:
Xiang W, Chen W. Persistent fetal vasculature with membranous cataract. Indian J Ophthalmol Case Rep 2021;1:454

How to cite this URL:
Xiang W, Chen W. Persistent fetal vasculature with membranous cataract. Indian J Ophthalmol Case Rep [serial online] 2021 [cited 2021 Jul 26];1:454. Available from: https://www.ijoreports.in/text.asp?2021/1/3/454/320083



A 5-month-old child presented to cataract clinic with leukokoria in one eye. Ocular examination showed diffuse white cataract combined with vessels in the lens material, which seemed like severe retinal detachment. Besides, small persistent pupillary membrane was observed [Figure 1]a, and posterior segment found no obvious abnormalities by ultrasonography. The patient underwent cataract surgery by using radiofrequency diathermy which greatly reduced bleeding, and histopathological examination revealed some hyperplastic and degenerative fibrovascular tissue combined with lymphocytes, and showed degenerative capsule tissues, while no lens cortex was found [Figure 1]b and [Figure 1]c. Therefore, a diagnosis of persistent fetal vasculature (PFV) combined with membranous cataract was made. PFV is a common ocular disease, and it may affect the anterior, retrolental, and/or posterior parts of the infant eye.[1] However, it is rare that PFV coexists with membranous cataract and blood vessels located in the lens.
Figure 1: (a) Anterior segment image showed dense white cataract combined with small persistent pupillary membrane and vessels in the lens material; (b and c) Histopathological examination by hematoxylin-eosin staining (×100 and ×200, respectively) demonstrated some hyperplastic and degenerative fibrovascular tissue combined with lymphocytes, and showed degenerative capsule tissues, while no lens cortex was found

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  References Top

1.
Goldberg MF. Persistent fetal vasculature (PFV): An integrated interpretation of signs and symptoms associated with persistent hyperplastic primary vitreous (PHPV). LIV Edward Jackson Memorial Lecture. Am J Ophthalmol 1997;124:587-626.  Back to cited text no. 1
    


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