|Year : 2021 | Volume
| Issue : 3 | Page : 454
Persistent fetal vasculature with membranous cataract
Wu Xiang, Weirong Chen
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China
|Date of Web Publication||02-Jul-2021|
Dr. Weirong Chen
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 7 Jinsui Road, Guangzhou - 510 623
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Xiang W, Chen W. Persistent fetal vasculature with membranous cataract. Indian J Ophthalmol Case Rep 2021;1:454
A 5-month-old child presented to cataract clinic with leukokoria in one eye. Ocular examination showed diffuse white cataract combined with vessels in the lens material, which seemed like severe retinal detachment. Besides, small persistent pupillary membrane was observed [Figure 1]a, and posterior segment found no obvious abnormalities by ultrasonography. The patient underwent cataract surgery by using radiofrequency diathermy which greatly reduced bleeding, and histopathological examination revealed some hyperplastic and degenerative fibrovascular tissue combined with lymphocytes, and showed degenerative capsule tissues, while no lens cortex was found [Figure 1]b and [Figure 1]c. Therefore, a diagnosis of persistent fetal vasculature (PFV) combined with membranous cataract was made. PFV is a common ocular disease, and it may affect the anterior, retrolental, and/or posterior parts of the infant eye. However, it is rare that PFV coexists with membranous cataract and blood vessels located in the lens.
|Figure 1: (a) Anterior segment image showed dense white cataract combined with small persistent pupillary membrane and vessels in the lens material; (b and c) Histopathological examination by hematoxylin-eosin staining (×100 and ×200, respectively) demonstrated some hyperplastic and degenerative fibrovascular tissue combined with lymphocytes, and showed degenerative capsule tissues, while no lens cortex was found|
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| References|| |
Goldberg MF. Persistent fetal vasculature (PFV): An integrated interpretation of signs and symptoms associated with persistent hyperplastic primary vitreous (PHPV). LIV Edward Jackson Memorial Lecture. Am J Ophthalmol 1997;124:587-626.