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CASE REPORT
Year : 2021  |  Volume : 1  |  Issue : 2  |  Page : 313-316

Rapidly progressing granulomatous retinochoroiditis with vasculitis: An extensive imaging and laboratory characterization of an unusual variant of sympathetic ophthalmia


1 Advanced Eye Center, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
2 Department of Ophthalmology, University Vita Salute, Hospital San Raffaele, Milano, Italy
3 Department of Immunopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
4 Department of Cytology and Gynecological Pathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
5 Department of Internal Medicine, Division of Rheumatology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
6 Department of Ophthalmology, West Coast Retina Medical Group, San Francisco, CA, USA

Correspondence Address:
Dr. Vishali Gupta
Professor of Ophthalmology, Advanced Eye Center, Post Graduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh - 160 012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_2047_20

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A 36-year-old male suffered a traumatic open globe injury to his right eye resulting in phthisis. One year later, he developed a sudden progressive decrease in vision in the fellow (left) eye. Examination revealed arteriolar attenuation, multifocal deep subretinal infiltration, retinal edema, and necrosis. The patient underwent diagnostic vitrectomy in the left eye, and diagnostic enucleation of the phthisical right eye after suboptimal response to intravenous corticosteroid, antiviral, and antibiotic therapy. Detailed immuno-histopathological evaluation revealed extensive retinal disorganization with photoreceptor loss, perivascular infiltration, Dalen-Fuchs nodules, and granulomatous inflammation with central necrosis and melanin pigment, suggestive of a rare variant of sympathetic ophthalmia.


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