|Year : 2021 | Volume
| Issue : 1 | Page : 37-38
Rapid Kayser-Fleischer ring following an embedded intracorneal copper foreign body
Ritu Arora, Jigyasa Sahu, Parul Jain, Shweta Viswanath
Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India
|Date of Submission||25-Apr-2020|
|Date of Acceptance||14-Jul-2020|
|Date of Web Publication||31-Dec-2020|
Dr. Jigyasa Sahu
A-24 Vrindavan Apartments, Sector-6 Plot-1 Dwarka New Delhi - 110 075
Source of Support: None, Conflict of Interest: None
Keywords: Chalcosis, intraocular copper foreign body, KF ring
|How to cite this article:|
Arora R, Sahu J, Jain P, Viswanath S. Rapid Kayser-Fleischer ring following an embedded intracorneal copper foreign body. Indian J Ophthalmol Case Rep 2021;1:37-8
|How to cite this URL:|
Arora R, Sahu J, Jain P, Viswanath S. Rapid Kayser-Fleischer ring following an embedded intracorneal copper foreign body. Indian J Ophthalmol Case Rep [serial online] 2021 [cited 2021 Mar 6];1:37-8. Available from: https://www.ijoreports.in/text.asp?2021/1/1/37/305476
A young male presented with a history of trauma to the right eye with a broken copper wire at his workplace four hours before; his visual acuity was 6/6. On slit-lamp biomicroscopy, a small piece of copper wire was found embedded within the deep stromal layer of the inferonasal cornea at a 5 o'clock location, 3 mm from the limbus [Figure 1]a, [Figure 1]b, [Figure 1]c. A greenish-brown mini ring (3.5 mm in diameter), consisting of deposited homogeneous material on the Descemet's membrane, was seen and confirmed by anterior segment optical coherence tomography (OCT) [Figure 1]d; no other abnormality was detected. A rust-colored, pointed foreign body was removed via the intracameral route using a foreign body forceps [Figure 2]a. Postoperatively, the patient was treated with topical prednisolone acetate 1% and topical moxifloxacin 0.5% (each applied 4 times a day). A scar remained at the site of the foreign body. However, the Kayser Fleischer (KF) ring persisted even at one month follow-up [Figure 2]b. The patient's unaided visual acuity continues to be 6/6.
|Figure 1: (a) Inferonasal intrastromal copper foreign body with surrounding KF ring, magnification x12. (b) Magnified image, magnification x20. (c) Slit image showing depth of foreign body, magnification x12. (d) Anterior segment optical coherence tomography image showing refractile foreign body in the deep stroma extending up to the endothelium, and a local adjacent rupture of Descemet's membrane and the endothelium with surrounding hyperreflectivity of the KF ring (white arrow)|
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|Figure 2: (a) The removed rust-coloured foreign body kept on a filter paper (black arrow). (b) Postoperative image showing scarring and opacity at the site of the foreign body removal and persistence of the ring|
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| Discussion|| |
The clinical picture arising from an intracorneal cuprous foreign body is diverse, ranging from no reaction to necrotic inflammation, and depends on the copper content. A ring-shaped deposition usually takes place, with chronic diffusion of metal from the retained corneal foreign body resulting in direct chalcosis of the cornea. A KF ring is most commonly seen in Wilson's disease, but can also be seen in chronic active hepatitis, primary biliary cirrhosis, hepatocellular disorders and due to the presence of an intracorneal copper-containing foreign body.
To our knowledge, there are no documented reports of intracorneal chalcosis or a pseudo KF ring within four hours of embedment of an intracorneal foreign body. High levels of copper and non- encapsulation possibly led to rapid development of the pseudo KF ring in our patient. This case highlights the need for an early removal of a deep- seated foreign body to avoid irreversible damage to corneal tissues.
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Conflicts of interest
There are no conflicts of interest.
| References|| |
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[Figure 1], [Figure 2]