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Year : 2021  |  Volume : 1  |  Issue : 1  |  Page : 14

Posterior lenticonus (lentiglobus) in a 13-year-old child

Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India

Date of Web Publication31-Dec-2020

Correspondence Address:
Dr. Parul Jain
Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi - 110 002
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_1703_20

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How to cite this article:
Jain P, Arora R. Posterior lenticonus (lentiglobus) in a 13-year-old child. Indian J Ophthalmol Case Rep 2021;1:14

How to cite this URL:
Jain P, Arora R. Posterior lenticonus (lentiglobus) in a 13-year-old child. Indian J Ophthalmol Case Rep [serial online] 2021 [cited 2021 Mar 6];1:14. Available from: https://www.ijoreports.in/text.asp?2021/1/1/14/305501

A 13-year-old male presented to the hospital complaining of bilateral cloudy vision since childhood. Ocular examination revealed best-corrected visual acuity (BCVA) of 20/60 bilaterally. Slit-lamp examination and biomicroscopy of both the eyes were within normal limits except for advanced posterior lenticonus. Oil droplet sign was appreciated on retroillumination [Figure 1]. A provisional diagnosis of Alport syndrome was made and the patient underwent a urine microscopic analysis for hematuria and renal ultrasonography. The child was not found to have any systemic comorbidity. The child was advised to undergo bilateral lens aspiration with intraocular lens (IOL) implantation to manage low vision. The prevalence of posterior lenticonus is estimated at 1–4 in 100,000 children.[1],[2]
Figure 1: Posterior lenticonus on retroillumination on slit-lamp examination

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Posterior lenticonus is characterized by a spherical deformity of the posterior surface of the lens. Clinically, an “oil droplet” red reflex is seen. Posterior lenticonus usually occurs as a sporadic, unilateral anomaly. Other, rare ocular associations include microphthalmos, microcornea, persistent anterior hyaloid vasculature, and uveal colobomas. Posterior lenticonus may also occur as a part of Alport syndrome and the oculocerebrorenal syndrome of Lowe. Any patient presenting with decreased vision and classical lentiglobus (posterior lenticonus) should be suspected to have systemic abnormalities and evaluated accordingly.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

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Conflicts of interest

There are no conflicts of interest.

  References Top

Colville DJ, Savige J. Alport syndrome: A review of the ocular manifestations. Ophthalmic Genet 1997;18:161-73.  Back to cited text no. 1
Vedantham V, Rajagopal J, Ratnagiri PK. Bilateral simultaneous anterior and posterior lenticonus in Alport's syndrome. Indian J Ophthalmol 2005;53:212-3.  Back to cited text no. 2
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